Het-PDB Navi2 (PDB: 6BKW)

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Ligands
Code	Name	Link
DXM	N-(3-{5-[(1,5-dimethyl-1h-pyrazol-3-yl)amino]-1-methyl-6-oxo-1,6-dihydropyridazin-3-yl}-2,6-difluorophenyl)-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide	PoSSuM
FPZ	Triphenylphosphane	PoSSuM
GOL	Glycerol	PoSSuM
SO4	Sulfate ion	PoSSuM

Non-standard Residues
Code	Name	Show
OCS	Cysteinesulfonic acid

Glycosylation
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Modification
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Download interaction data: 6BKW

Code :

6BKW PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

BTK complex with compound 12

Release Data :

2018-11-07

Compound :

mol_id	molecule	chains	synonym
1	Tyrosine-protein kinase BTK	A	Agammaglobulinemia tyrosine kinase,ATK,B-cell progenitor kinase,BPK,Bruton tyrosine kinase
	ec: 2.7.10.2

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Spodoptera frugiperda (taxid:7108)
	gene: BTK, AGMX1, ATK, BPK

Authors :

Kiefer, J.R., Eigenbrot, C., Yu, C.L.

Keywords :

BTK, inhibitor, water structure, kinase, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 1.4990 Å )

Citation :

Water molecules in protein-ligand interfaces. Evaluation of software tools and SAR comparison.

Nittinger, E.,Gibbons, P.,Eigenbrot, C. et al.
(2019) J. Comput. Aided Mol. Des. 33 : 307 - 330

PDB ID: 6BKW