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Ligands
Code Name Style Show Link
ADP Adenosine-5'-diphosphate
CZJ (3s,5s,7s)-N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2h-1-ben zopyran-3-yl}tricyclo[3.3.1.1~3,7~]decane-1-carboxamide
MG Magnesium ion
Non-standard Residues
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Glycosylation
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Code : 6B8B   PDBj   RCSB PDB   PDBe
Header : lipid transport/activator
Title : E. coli LptB in complex with ADP and a novobiocin derivative
Release Data : 2017-12-06
Compound :
mol_id molecule chains
1 Lipopolysaccharide export system ATP-binding protein LptB A
ec: 3.6.3.-
Source :
mol_id organism_scientific expression_system
1 Escherichia coli (strain K12)  (taxid:83333) Escherichia coli KRX  (taxid:1452720)
strain: K12
gene: lptB, yhbG, b3201, JW3168
Authors : Mandler, M.D., Owens, T.W., Lazarus, M.B., May, J.M., Kahne, D.K.
Keywords : LptB, ABC transporter, LPS transport, LIPID TRANSPORT, lipid transport-activator complex
Exp. method : X-RAY DIFFRACTION ( 1.9500 Å )
Citation :

The Antibiotic Novobiocin Binds and Activates the ATPase That Powers Lipopolysaccharide Transport.

May, J.M.,Owens, T.W.,Mandler, M.D.  et al.
(2017)  J. Am. Chem. Soc.  139 : 17221 - 17224

PubMed: 29135241
DOI: 10.1021/jacs.7b07736

Chain : A
UniProt : P0A9V1 (LPTB_ECOLI)
Reaction : -