PDB ID: 6B73
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Code | Name | Style | Show | Link | |
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CVV | N-[(5alpha,6beta)-17-(cyclopropylmethyl)-3-hydroxy-7,8-didehydro-4,5-epoxymorphinan-6-yl]-3-iodobenzamide | PoSSuM | |||
CLR | Cholesterol | PoSSuM | |||
OLA | Oleic acid | PoSSuM |
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Download interaction data: 6B73
Structure summary
Code : | 6B73 PDBj RCSB PDB PDBe | ||||||||||||||||||||
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Header : | MEMBRANE PROTEIN/AGONIST | ||||||||||||||||||||
Title : | Crystal Structure of a nanobody-stabilized active state of the kappa-opioid receptor | ||||||||||||||||||||
Release Data : | 2018-01-17 | ||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Che, T., Majumdar, S., Zaidi, S.A., Kormos, C., McCorvy, J.D., Wang, S., Mosier, P.D., Uprety, R., Vardy, E., Krumm, B.E., Han, G.W., Lee, M.Y., Pardon, E., Steyaert, J., Huang, X.P., Strachan, R.T., Tribo, A.R., Pasternak, G.W., Carroll, I.F., Stevens, R.C., Cherezov, V., Katritch, V., Wacker, D., Roth, B.L. | ||||||||||||||||||||
Keywords : | GPCR, opioid receptor, addiction, active state, nanobody, structure-function, morphinan, LCP, membrane protein, MEMBRANE PROTEIN-AGONIST complex | ||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.10 Å ) | ||||||||||||||||||||
Citation : |
Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.
Che, T.,Majumdar, S.,Zaidi, S.A.
et al.
PubMed: 29307491 |
Reaction
Chain : | A, B |
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UniProt : | P0ABE7 (C562_ECOLX) |
Reaction : | - |
Chain : | A, B |
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UniProt : | P41145 (OPRK_HUMAN) |
Reaction : | - |