Brand  (β version)

color scheme of protein:

chain: Hide other chain(s)

Modified Residues
Code Name Link
CGY (1r)-1,4-anhydro-2-deoxy-1-[2,6-diamino-5-(dihydroxyamino)pyridin-3-yl]-5-O-phosphono-D-erythro-pentitol
Code : 6B1S
Header : DNA BINDING PROTEIN/DNA
Title : Hydrogen Bonding Complementary, not size complementarity is key in the formation of the double helix
Release Data : 2018-09-19
Compound :
mol_id molecule chains
1 Reverse transcriptase A,B
ec: 2.7.7.49
fragment: Catalytic fragment (UNP residues 683-937)
mol_id molecule chains
2 DNA (5'-D(*CP*TP*TP*AP*TP*AP*(CGY)P*(CGY)P*TP*TP*TP*AP*TP*AP*AP*G)-3') E,F
Source :
mol_id organism_scientific organism_common expression_system
1 Moloney murine leukemia virus  (taxid:11801) MoMLV Escherichia coli  (taxid:562)
mol_id organism_scientific
2 Escherichia coli  (taxid:562)
synthetic: yes
Authors : Singh, I., Georgiadis, M.M.
Keywords : Protein-DNA, AEGIS, unnatural base pair, host-guest system, DNA BINDING PROTEIN, DNA BINDING PROTEIN-DNA complex
Exp. method : X-RAY DIFFRACTION ( 2.000 Å )
Citation :

"Skinny" and "Fat" DNA: Two New Double Helices.

Hoshika, S.,Singh, I.,Switzer, C.  et al.
(2018)  J. Am. Chem. Soc.  140 : 11655 - 11660

PubMed: 30148365
DOI: 10.1021/jacs.8b05042

Chain : A, B
UniProt : P03355 (POL_MLVMS)
Reaction : Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
Endonucleolytic cleavage to 5'- phosphomonoester.