Het-PDB Navi2 (PDB: 6B0T)

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Ligands
Code	Name		Style	Show	Link
C7V	4-methyl-N-(1-{[4-(trifluoromethyl)phenyl]methyl}-1h-indazol-3-yl)-1,2-oxazole-5-carboxamide				PoSSuM

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Download interaction data: 6B0T

Code :

6B0T PDBj RCSB PDB PDBe

Header :

PROTEIN BINDING

Title :

Structural Insights into the Induced-fit Inhibition of Fascin by a Small Molecule

Release Data :

2018-04-18

Compound :

mol_id	molecule	chains	synonym
1	Fascin	A,B,C,D,E,F	55 kDa actin-bundling protein,Singed-like protein,p55
	fragment: residues 7-493

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: FSCN1, FAN1, HSN, SNL

Authors :

Dey, R., Huang, X.Y.

Keywords :

Metastaic cancers, Small-molecule inhibitors, actin-bundling, Domain rotation, PROTEIN BINDING

Exp. method :

X-RAY DIFFRACTION ( 2.800 Å )

Citation :

Structural Insights into the Induced-fit Inhibition of Fascin by a Small-Molecule Inhibitor.

Huang, J.,Dey, R.,Wang, Y. et al.
(2018) J. Mol. Biol. 430 : 1324 - 1335

PDB ID: 6B0T