PDB ID: 6AZV
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Structure summary
Code : | 6AZV PDBj RCSB PDB PDBe | ||||||||||||
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Header : | oxidoreductase/oxidoreductase inhibitor | ||||||||||||
Title : | IDO1/BMS-978587 crystal structure | ||||||||||||
Release Data : | 2018-03-21 | ||||||||||||
Compound : |
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Source : |
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Authors : | Lewis, H.A. | ||||||||||||
Keywords : | IDO1 heme-displaced ligand-bound, oxidoreductase-oxidoreductase inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.7550 Å ) | ||||||||||||
Citation : |
Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form.
Nelp, M.T.,Kates, P.A.,Hunt, J.T.
et al.
PubMed: 29531094 |
Reaction
Chain : | A, B, C, D | ||||||||||||
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UniProt : | P14902 (I23O1_HUMAN) | ||||||||||||
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