Brand  (β version)

PDB ID: 6AGF

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Ligands
Code Name Style Show Link
6OU [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{z})-octadec-9-enoate PoSSuM
9Z9 (3beta,14beta,17beta,25r)-3-[4-methoxy-3-(methoxymethyl)butoxy]spirost-5-en PoSSuM
Non-standard Residues
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Glycosylation
Code Name Emphasize
BMA Beta-D-mannopyranose
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
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Structure summary

Code : 6AGF   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta1
Release Data : 2018-10-10
Compound :
mol_id molecule chains synonym
1 Sodium channel protein type 4 subunit alpha A SkM1,Sodium channel protein skeletal muscle subunit alpha,Sodium channel protein type IV subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.4
mol_id molecule chains
2 Sodium channel subunit beta-1 B
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Homo sapiens  (taxid:9606)
gene: SCN4A
mol_id organism_scientific organism_common expression_system
2 Homo sapiens  (taxid:9606) Human Homo sapiens  (taxid:9606)
gene: SCN1B
Authors : Pan, X.J., li, Z.Q., Zhou, Q., Shen, H.Z., Wu, K., Huang, X.S., Chen, J.F., Zhang, J.R., Zhu, X.C., Lei, J.L., Xiong, W., Gong, H.P., Xiao, B.L., Yan, N.
Keywords : sodium channel, MEMBRANE PROTEIN
Exp. method : ELECTRON MICROSCOPY ( 3.2 Å )
Citation :

Structure of the human voltage-gated sodium channel Nav1.4 in complex with beta 1.

Pan, X.,Li, Z.,Zhou, Q.  et al.
(2018)  Science  362

PubMed: 30190309
DOI: 10.1126/science.aau2486

Reaction

Chain : A
UniProt : P35499 (SCN4A_HUMAN)
Reaction : -
Chain : B
UniProt : Q07699 (SCN1B_HUMAN)
Reaction : -