Het-PDB Navi2 (PDB: 6A95)

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Ligands
Code	Name		Style	Show	Link
9SR	(1r,5r,6r,7r,9s,11s,12s,13s,14s)-3-amino-14-(hydroxymethyl)-8,10-dioxa-2,4-diazatetracyclo[7.3.1.1~7,11~.0~1,6~]tetradec-3-ene-5,9,12,13,14-pentol (non-preferred name)				PoSSuM
NA	Sodium ion				PoSSuM

Non-standard Residues
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Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
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Download interaction data: 6A95

Code :

6A95 PDBj RCSB PDB PDBe

Header :

MEMBRANE PROTEIN/TOXIN

Title :

Complex of voltage-gated sodium channel NavPaS from American cockroach Periplaneta americana bound with tetrodotoxin and Dc1a

Release Data :

2018-08-08

Compound :

mol_id	molecule	chains	synonym
1	Sodium channel protein PaFPC1	A	Voltage-gated sodium channel,PaFPC1,NavPaS

mol_id	molecule	chains	synonym
2	Mu-diguetoxin-Dc1a	B	Mu-DGTX-Dc1a,Insecticidal toxin DTX9.2

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Periplaneta americana (taxid:6978)	American cockroach	Homo sapiens (taxid:9606)

mol_id	organism_scientific	organism_common	expression_system
2	Diguetia canities (taxid:38407)	Desert bush spider	Escherichia coli (taxid:562)

Authors :

Shen, H.Z., li, Z.Q., Jiang, Y., Pan, X.J., Wu, J.P., Cristofori-Armstrong, B., Smith, J.J., Chin, Y.K.Y., Lei, J.L., Zhou, Q., King, G.F., Yan, N.

Keywords :

complex, sodium channel, toxin, MEMBRANE PROTEIN, MEMBRANE PROTEIN-TOXIN complex

Exp. method :

ELECTRON MICROSCOPY ( 2.6 Å )

Citation :

Structural basis for the modulation of voltage-gated sodium channels by animal toxins.

Shen, H.,Li, Z.,Jiang, Y. et al.
(2018) Science 362

PDB ID: 6A95