Brand  (β version)

PDB ID: 6A88

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
ANP Phosphoaminophosphonic acid-adenylate ester PoSSuM
MG Magnesium ion PoSSuM
9SF 3-{3-[(2r,3s)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3h)-one PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 6A88   PDBj   RCSB PDB   PDBe
Header : TRANSLATION
Title : Crystal Structure of T. gondii prolyl tRNA synthetase with Febrifugine and ATP Analog
Release Data : 2019-10-23
Compound :
mol_id molecule chains
1 Prolyl-tRNA synthetase (ProRS) A,B,C,D
ec: 6.1.1.15
fragment: UNP residues 334-830
Source :
mol_id organism_scientific expression_system
1 Toxoplasma gondii ME49  (taxid:508771) Escherichia coli  (taxid:562)
strain: Me49
gene: TGME49_219850
Authors : Kumari, S., Mishra, S., Yogavel, M., Sharma, A.
Keywords : PRS, Drug, Parasite, ATP, TRANSLATION
Exp. method : X-RAY DIFFRACTION ( 2.5960 Å )
Citation :

Conformational heterogeneity in apo and drug-bound structures of Toxoplasma gondii prolyl-tRNA synthetase.

Mishra, S.,Malhotra, N.,Kumari, S.  et al.
(2019)  Acta Crystallogr.,Sect.F  75 : 714 - 724

PubMed: 31702585
DOI: 10.1107/S2053230X19014808

Reaction

Chain : A, B, C, D
UniProt : S8G8I1 (S8G8I1_TOXGM)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl- tRNA(Pro) 6.1.1.15 ARBA:ARBA00000857
-