Brand  (β version)

PDB ID: 5ZSJ

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Ligands
Code Name Style Show Link
9JR 4-azanyl-2-butoxy-8-[[3-(pyrrolidin-1-ylmethyl)phenyl]methyl]-5,7-dihydropteridin-6-one PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
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Glycosylation
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NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
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Structure summary

Code : 5ZSJ   PDBj   RCSB PDB   PDBe
Header : IMMUNE SYSTEM
Title : Crystal structure of monkey TLR7 in complex with GS9620
Release Data : 2019-01-30
Compound :
mol_id molecule chains
1 Toll-like receptor 7 A,B
fragment: UNP residues 28-839
mutation: N167Q,N389Q,N488Q,N799Q
Source :
mol_id organism_scientific organism_common expression_system
1 Macaca mulatta  (taxid:9544) Rhesus macaque Drosophila melanogaster  (taxid:7227)
gene: TLR7
Authors : Zhang, Z., Ohto, U., Shimizu, T.
Keywords : Innate immunity Toll-like receptors, IMMUNE SYSTEM
Exp. method : X-RAY DIFFRACTION ( 2.400 Å )
Citation :

Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands.

Zhang, Z.,Ohto, U.,Shibata, T.  et al.
(2018)  Cell Rep  25 : 3371 - 3381.e5

PubMed: 30566863
DOI: 10.1016/j.celrep.2018.11.081

Reaction

Chain : A, B
UniProt : B3Y653 (B3Y653_MACMU)
Reaction : -