PDB ID: 5ZQQ
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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9H6 | 1-methyl-1'-(4-oxo-3,4,5,6,7,8-hexahydroquinazolin-2-yl)spiro[indole-3,4'-piperidin]-2(1h)-one | PoSSuM | |||
GOL | Glycerol | PoSSuM | |||
PO4 | Phosphate ion | PoSSuM | |||
ZN | Zinc ion | PoSSuM |
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Download interaction data: 5ZQQ
Structure summary
Code : | 5ZQQ PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||||||||||||||
Title : | Tankyrase-2 in complex with compound 52 | ||||||||||||||||||||||||
Release Data : | 2019-04-03 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Niwa, H., Shirai, F., Sato, S., Yoshimoto, N., Tsumura, T., Okue, M., Shirouzu, M., Seimiya, H., Umehara, T. | ||||||||||||||||||||||||
Keywords : | Tankyrase, PARP, ADP-ribosylation, Transferase-transferase inhibitor complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.29 Å ) | ||||||||||||||||||||||||
Citation : |
Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors.
Shirai, F.,Tsumura, T.,Yashiroda, Y.
et al.
PubMed: 30883102 |
Reaction
Chain : | B | ||||||||||||||||
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UniProt : | Q9H2K2 (TNKS2_HUMAN) | ||||||||||||||||
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