Het-PDB Navi2 (PDB: 5ZKP)

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Ligands
Code	Name		Style	Show	Link
9ER	N1,n1-dimethyl-n2-[(pyridin-3-yl)methyl]-n2-{4-[2,4,6-tri(propan-2-yl)phenyl]-1,3-thiazol-2-yl}ethane-1,2-diamine				PoSSuM
FMN	Flavin mononucleotide				PoSSuM

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Download interaction data: 5ZKP

Code :

5ZKP PDBj RCSB PDB PDBe

Header :

SIGNALING PROTEIN

Title :

Crystal structure of the human platelet-activating factor receptor in complex with SR 27417

Release Data :

2018-06-20

Compound :

mol_id	molecule	chains	synonym
1	Platelet-activating factor receptor,Flavodoxin,Platelet-activating factor receptor	A	PAFr,PAFr
	mutation: F116Y, N169D,P2A, Y98W,A230D, V234A, D289N other_details: The fusion protein of Platelet-activating factor receptor (UNP residues 2-216), Flavodoxin (UNP residues 2-148), Platelet-activating factor receptor (UNP residues 224-316), and tags

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Spodoptera frugiperda (taxid:7108)
	strain: Hildenborough / ATCC 29579 / DSM 644 / NCIMB 8303 gene: PTAFR, PAFR

Authors :

Cao, C., Zhao, Q., Zhang, X.C., Wu, B.

Keywords :

G protein-coupled receptor, Platelet-activating factor receptor, Complex, SIGNALING PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.81 Å )

Citation :

Structural basis for signal recognition and transduction by platelet-activating-factor receptor.

Cao, C.,Tan, Q.,Xu, C. et al.
(2018) Nat. Struct. Mol. Biol. 25 : 488 - 495

Chain :

UniProt :

P00323 (FLAV_NITV2)

Cofactor:	Evidence:	Note:
Reaction :	-
FMN	-	-

PDB ID: 5ZKP