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Ligands
Code Name Style Show Link
9AF Dimethyl 4-{3-[({3-[4-(3-methoxyphenyl)piperidin-1-yl]propyl}carbamoyl)amino]phenyl}-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Non-standard Residues
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Code : 5ZBH   PDBj   RCSB PDB   PDBe
Header : SIGNALING PROTEIN
Title : The Crystal Structure of Human Neuropeptide Y Y1 Receptor with BMS-193885
Release Data : 2018-04-25
Compound :
mol_id molecule chains synonym
1 Neuropeptide Y receptor type 1,T4 Lysozyme,Neuropeptide Y receptor type 1 A NPY1-R,Lysis protein,Lysozyme,Muramidase,NPY1-R
ec: 3.2.1.17
fragment: UNP residues 2-241,UNP residues 2-161,UNP residues 250-358
mutation: F129W,C1053T, C1096A
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
gene: NPY1R, NPYR, NPYY1
Authors : Yang, Z., Han, S., Zhao, Q., Wu, B.
Keywords : G Protein-Coupled Receptor Neuropeptide Y Y1 Receptor Inhibitor Complex structure, SIGNALING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 3.00 Å )
Citation :

Structural basis of ligand binding modes at the neuropeptide Y Y1receptor

Yang, Z.,Han, S.,Keller, M.  et al.
(2018)  Nature  556 : 520 - 524

PubMed: 29670288
DOI: 10.1038/s41586-018-0046-x

Chain : A
UniProt : P25929 (NPY1R_HUMAN)
Reaction : -
Chain : A
UniProt : D9IEF7 (D9IEF7_BPT4)
Reaction: EC: Evidence:
Physiological Direction:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. 3.2.1.17 ARBA:ARBA00000632, HAMAP-Rule:MF_04110, RuleBase:RU003788
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