Het-PDB Navi2 (PDB: 5Z8A)

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Ligands
Code	Name		Style	Show	Link
JIA	(2~{R},3~{R},4~{R},5~{R})-2-[(1~{S},2~{S},3~{R},4~{S},6~{R})-3-[(2~{R},3~{R},4~{R},5~{S},6~{R})-6-(aminomethyl)-3-azany L-4,5-bis(oxidanyl)oxan-2-yl]oxy-4,6-bis(azanyl)-2-oxidanyl-cyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol				PoSSuM
PLP	Pyridoxal-5'-phosphate				PoSSuM

Non-standard Residues
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Download interaction data: 5Z8A

Code :

5Z8A PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Crystal structure of GenB1 from Micromonospora echinospora in complex with JI-20A and PLP (external aldimine)

Release Data :

2019-01-16

Compound :

mol_id	molecule	chains	synonym
1	C-6' aminotransferase	A,B	Gentamicin (Hexosaminyl-6-) aminotransferase I,GntW,Putative glutamate-1-semialdehyde aminotransferase

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Micromonospora echinospora (taxid:1877)	Micromonospora purpurea	Escherichia coli (taxid:562)
	gene: gacK, genB1, gntW

Authors :

Hong, S.K., Cha, S.S.

Keywords :

Aminotransferase, PLP-binding, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 1.3980 Å )

Citation :

Complete reconstitution of the diverse pathways of gentamicin B biosynthesis.

Ban, Y.H.,Song, M.C.,Hwang, J.Y. et al.
(2019) Nat. Chem. Biol. 15 : 295 - 303

Chain :

A, B

UniProt :

Q70KD9 (Q70KD9_MICEC)

Cofactor:	Evidence:	Note:
Reaction :	-
pyridoxal 5'-phosphate	ECO:0000256 \| ARBA:ARBA00001933	-

PDB ID: 5Z8A