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Ligands
Code Name Style Show Link
JX1 N-[4-(4-methoxyphenyl)-3-[5-(8-methylquinolin-5-yl)-2,4-bis(oxidanyl)phenyl]-1,2-oxazol-5-yl]ethanamide
Non-standard Residues
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Code : 5XRE   PDBj   RCSB PDB   PDBe
Header : CHAPERONE
Title : Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor JX1
Release Data : 2018-07-04
Compound :
mol_id molecule chains synonym
1 Heat shock protein HSP 90-alpha A Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38
fragment: UNP RESIDUES 9-236
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: HSP90AA1, HSP90A, HSPC1, HSPCA
Authors : Li, J., Shi, F., Xiong, B., He, J.H.
Keywords : Heat shock protein HSP 90, CHAPERONE
Exp. method : X-RAY DIFFRACTION ( 1.497 Å )
Citation :

Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor JX1

Li, J.,Shi, F.,Xiong, B.  et al.
To Be Published 

Chain : A
UniProt : P07900 (HS90A_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
ATP + H2O = ADP + H(+) + phosphate 3.6.4.10 PubMed:12526792
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