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Ligands
Code Name Style Show Link
CAH 5-exo-hydroxycamphor
HEM Protoporphyrin ix containing Fe
K Potassium ion
Non-standard Residues
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Glycosylation
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Code : 5WK7   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : P450cam mutant R186A
Release Data : 2017-09-06
Compound :
mol_id molecule chains synonym
1 Camphor 5-monooxygenase A Cytochrome P450-cam,Cytochrome P450cam
ec: 1.14.15.1
mutation: R186A, C334A
Source :
mol_id organism_scientific expression_system
1 Pseudomonas putida  (taxid:303) Escherichia coli  (taxid:562)
gene: camC, cyp101
Authors : Batabyal, D., Poulos, T.L.
Keywords : salt bridge interaction, proton coupled electron transfer, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.983 Å )
Citation :

Effect of Redox Partner Binding on Cytochrome P450 Conformational Dynamics.

Batabyal, D.,Richards, L.S.,Poulos, T.L.
(2017)  J. Am. Chem. Soc.  139 : 13193 - 13199

PubMed: 28823160
DOI: 10.1021/jacs.7b07656

Chain : A
UniProt : P00183 (CPXA_PSEPU)
Reaction: EC: Evidence:
Physiological Direction:
(1R,4R)-camphor + 2 H(+) + O2 + 2 reduced [2Fe-2S]- [putidaredoxin] = (1R,4R,5R)-5-hydroxycamphor + H2O + 2 oxidized [2Fe-2S]-[putidaredoxin] 1.14.15.1 -
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