Het-PDB Navi2 (PDB: 5VT4)

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Ligands
Code	Name		Style	Show	Link
9KJ	{[(2r,3r,4r,5r)-3-(alpha-D-glucopyranosyloxy)-4-hydroxy-2,5-bis(hydroxymethyl)pyrrolidin-1-yl]methyl}phosphonic acid				PoSSuM

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Glycosylation
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Download interaction data: 5VT4

Code :

5VT4 PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Sco GlgEI-V279S in complex with a pyrolidene-based methyl-phosphonate compound

Release Data :

2017-06-07

Compound :

mol_id	molecule	chains	synonym
1	Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1	A,B,C,D	GMPMT 1,(1->4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase 1
	ec: 2.4.99.16 mutation: V279S

Source :

mol_id	organism_scientific	expression_system
1	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (taxid:100226)	Escherichia coli (taxid:562)
	strain: ATCC BAA-471 / A3(2) / M145 gene: glgE1, pep1, pep1A, pep1I, SCO5443, SC6A11.19c expression_system_cell: BL21 expression_system_plasmid: pET32

Authors :

Petit, C., Ronning, D.R., Lindenberger, J.J.

Keywords :

Streptomyces coelicolor, Maltosyltransferase, transition state analogue, Alpha-1, 4-glucan, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 3.205 Å )

Citation :

Zwitterionic pyrrolidene-phosphonates: inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S.

Veleti, S.K.,Petit, C.,Ronning, D.R. et al.
(2017) Org. Biomol. Chem. 15 : 3884 - 3891

Chain :

A, B, C, D

UniProt :

Q9L1K2 (GLGE1_STRCO)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
[(1->4)-alpha-D-glucosyl](n) + alpha-maltose 1-phosphate = [(1->4)-alpha-D-glucosyl](n+2) + phosphate	2.4.99.16	PubMed:21914799
	-	PubMed:21914799

PDB ID: 5VT4