PDB ID: 5QFT
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Structure summary
Code : | 5QFT PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMSOA000683b | ||||||||||||
Release Data : | 2018-10-10 | ||||||||||||
Compound : |
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Authors : | Keedy, D.A., Hill, Z.B., Biel, J.T., Kang, E., Rettenmaier, T.J., Brandao-Neto, J., von Delft, F., Wells, J.A., Fraser, J.S. | ||||||||||||
Keywords : | PanDDA, SGC - Diamond I04-1 fragment screening, protein tyrosine phosphatase, PTP, protein tyrosine phosphatase 1B, PTP1B, enzyme, allostery, multiconformer, HYDROLASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.9600 Å ) | ||||||||||||
Citation : |
An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
Keedy, D.A.,Hill, Z.B.,Biel, J.T.
et al.
PubMed: 29877794 |
Reaction
Chain : | A | ||||||||
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UniProt : | P18031 (PTN1_HUMAN) | ||||||||
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