PDB ID: 5QFH
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
JOD | (5s,8r,8as)-8-hydroxyhexahydro-3h-5,8-ethano[1,3]oxazolo[3,4-a]pyridin-3-one | PoSSuM | |||
TRS | 2-amino-2-hydroxymethyl-propane-1,3-diol | PoSSuM |
Code | Name | Show |
---|
Code | Name | Emphasize |
---|
Code | Name | Show |
---|
Download interaction data: 5QFH
Structure summary
Code : | 5QFH PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | HYDROLASE | ||||||||||||
Title : | PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOOA000525a | ||||||||||||
Release Data : | 2018-10-10 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Keedy, D.A., Hill, Z.B., Biel, J.T., Kang, E., Rettenmaier, T.J., Brandao-Neto, J., von Delft, F., Wells, J.A., Fraser, J.S. | ||||||||||||
Keywords : | PanDDA, SGC - Diamond I04-1 fragment screening, protein tyrosine phosphatase, PTP, protein tyrosine phosphatase 1B, PTP1B, enzyme, allostery, multiconformer, HYDROLASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.5910 Å ) | ||||||||||||
Citation : |
An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering.
Keedy, D.A.,Hill, Z.B.,Biel, J.T.
et al.
PubMed: 29877794 |
Reaction
Chain : | A | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | P18031 (PTN1_HUMAN) | ||||||||
|