PDB ID: 5OS8
Hetero Atom Contents
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Color scheme of protein:
Code | Name | Style | Show | Link | |
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ACT | Acetate ion | PoSSuM | |||
ATP | Adenosine-5'-triphosphate | PoSSuM | |||
DMS | Dimethyl sulfoxide | PoSSuM | |||
J27 | [3-chloranyl-4-(4-fluoranyl-2-methyl-phenyl)phenyl]methylazanium | PoSSuM |
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Download interaction data: 5OS8
Structure summary
Code : | 5OS8 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | The crystal structure of CK2alpha in complex with compound 11 | ||||||||||||
Release Data : | 2018-02-28 | ||||||||||||
Compound : |
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Source : |
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Authors : | Brear, P., De Fusco, C., Iegre, J., Yoshida, M., Mitchell, S., Rossmann, M., Carro, L., Sore, H., Hyvonen, M., Spring, D. | ||||||||||||
Keywords : | CK2alpha, CK2a, fragment based drug discovery, high concentration screening, selective ATP competitive inhibitors, surface entrophy reduction, Transferase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.5500 Å ) | ||||||||||||
Citation : |
Second-generation CK2 alpha inhibitors targeting the alpha D pocket.
Iegre, J.,Brear, P.,De Fusco, C.
et al.
PubMed: 29732088 |
Reaction
Chain : | A | ||||||||||||||
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UniProt : | P68400 (CSK21_HUMAN) | ||||||||||||||
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