PDB ID: 5OHJ
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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ZN | Zinc ion | PoSSuM | |||
MG | Magnesium ion | PoSSuM | |||
9VE | [(1~{S})-2-[3,5-bis(chloranyl)-1-oxidanyl-pyridin-1-ium-4-yl]-1-[4-[bis(fluoranyl)methoxy]-3-(cyclopropylmethoxy)phenyl]ethyl] (2~{S})-1-[3-(dimethylcarbamoyl)phenyl]sulfonylpyrrolidine-2-carboxylate | PoSSuM |
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Download interaction data: 5OHJ
Structure summary
Code : | 5OHJ PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Human phosphodiesterase 4B catalytic domain in complex with a pyrrolidinyl inhibitor. | ||||||||||||
Release Data : | 2017-12-13 | ||||||||||||
Compound : |
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Authors : | Rizzi, A., Carzaniga, L., Armani, E. | ||||||||||||
Keywords : | human phosphodiesterase 4B, hydrolase, pyrrolidinyl inhibitor, PDE4B | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.60 Å ) | ||||||||||||
Citation : |
Discovery and Optimization of Thiazolidinyl and Pyrrolidinyl Derivatives as Inhaled PDE4 Inhibitors for Respiratory Diseases.
Carzaniga, L.,Amari, G.,Rizzi, A.
et al.
PubMed: 29200281 |
Reaction
Chain : | A, B | ||||||||
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UniProt : | Q07343 (PDE4B_HUMAN) | ||||||||
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