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Ligands
Code Name Style Show Link
NAP Nadp nicotinamide-adenine-dinucleotide phosphate
9RH 2,2,2-trifluoromethyl acetophenone hydrate
MG Magnesium ion
Non-standard Residues
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Glycosylation
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Code : 5OCM   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Imine Reductase from Streptosporangium roseum in complex with NADP+ and 2,2,2-trifluoroacetophenone hydrate
Release Data : 2018-05-16
Compound :
mol_id molecule chains synonym
1 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase A,B,C,D,E,F Imine Reductase
Source :
mol_id organism_scientific expression_system
1 Streptosporangium roseum  (taxid:2001) Escherichia coli BL21(DE3)  (taxid:469008)
gene: Sros_0924
expression_system_vector_type: Plasmid
expression_system_vector: pET-28a
Authors : Sharma, M., Nestl, B., Grogan, G.
Keywords : Imine, Amine, NADPH, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.81 Å )
Citation :

New imine-reducing enzymes from beta-hydroxyacid dehydrogenases by single amino acid substitutions.

Lenz, M.,Fademrecht, S.,Sharma, M.  et al.
(2018)  Protein Eng. Des. Sel.  31 : 109 - 120

PubMed: 29733377
DOI: 10.1093/protein/gzy006

Chain : A, B, C, D, E, F
UniProt : D2B7Z8 (D2B7Z8_STRRD)
Reaction : -