PDB ID: 5OC8
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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9QW | (4~{S})-5-(5-chloranyl-1-methyl-2-oxidanylidene-pyridin-3-yl)-4-(4-chlorophenyl)-2-(2,4-dimethoxypyrimidin-5-yl)-3-propan-2-yl-4~{H}-pyrrolo[3,4-D]imidazol-6-one | PoSSuM | |||
CL | Chloride ion | PoSSuM |
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Download interaction data: 5OC8
Structure summary
Code : | 5OC8 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | LIGASE | ||||||||||||
Title : | HDM2 (17-111, WILD TYPE) COMPLEXED WITH NVP-HDM201 AT 1.56A | ||||||||||||
Release Data : | 2018-08-22 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kallen, J. | ||||||||||||
Keywords : | PPI WITH P53, INHIBITOR COMPLEX, CELL CYCLE, LIGASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.5600 Å ) | ||||||||||||
Citation : |
Dose and Schedule Determine Distinct Molecular Mechanisms Underlying the Efficacy of the p53-MDM2 Inhibitor HDM201.
Jeay, S.,Ferretti, S.,Holzer, P.
et al.
PubMed: 30135191 |
Reaction
Chain : | A | ||||||||
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UniProt : | Q00987 (MDM2_HUMAN) | ||||||||
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