PDB ID: 5O91
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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C5N | ~{N}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-H]quinazoline-3-carboxamide | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM |
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Download interaction data: 5O91
Structure summary
Code : | 5O91 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of human Mps1 (TTK) C604W mutant in complex with Cpd-5 | ||||||||||||
Release Data : | 2017-07-26 | ||||||||||||
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Authors : | Hiruma, Y., Joosten, R.P., Perrakis, A. | ||||||||||||
Keywords : | Mps1, TTK, kinase, inhibitor, Cpd-5, mutant, C604W, transferase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.2000 Å ) | ||||||||||||
Citation : |
Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.
Hiruma, Y.,Koch, A.,Hazraty, N.
et al.
PubMed: 28726638 |
Reaction
Chain : | A | ||||||||||||||||
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UniProt : | P33981 (TTK_HUMAN) | ||||||||||||||||
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