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Ligands
Code Name Style Show Link
EDO 1,2-ethanediol
J6W (5-methyl-1-benzothiophen-2-yl)methanol
Non-standard Residues
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Glycosylation
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Code : 5MWO   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION
Title : Structure of Mycobacterium Tuberculosis Transcriptional Regulatory Repressor Protein (EthR) in complex with fragment 7E8.
Release Data : 2017-05-31
Compound :
mol_id molecule chains
1 HTH-type transcriptional regulator EthR A
Source :
mol_id organism_scientific expression_system
1 Mycobacterium tuberculosis H37Rv  (taxid:83332) Escherichia coli  (taxid:562)
gene: ethR, etaR, Rv3855
expression_system_variant: DH5a
Authors : Mendes, V., Chan, D.S.-H., Thomas, S.E., McConnell, B., Matak-Vinkovic, D., Coyne, A.G., Abell, C., Blundell, T.L.
Keywords : EthR, Repressor, TetR, Mycobacterium tuberculosis, Transcription
Exp. method : X-RAY DIFFRACTION ( 1.9620 Å )
Citation :

Fragment Screening against the EthR-DNA Interaction by Native Mass Spectrometry.

Chan, D.S.,Mendes, V.,Thomas, S.E.  et al.
(2017)  Angew. Chem. Int. Ed. Engl.  56 : 7488 - 7491

PubMed: 28513917
DOI: 10.1002/anie.201702888

Chain : A
UniProt : P9WMC1 (ETHR_MYCTU)
Reaction : -