PDB ID: 5MIM
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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1N | 1-[(1~{R},2~{R},4~{S},5~{S})-2,4-bis(4-carbamimidamidophenoxy)-5-[(4-carbamimidamidophenyl)amino]cyclohexyl]guanidine | PoSSuM | |||
CA | Calcium ion | PoSSuM | |||
CL | Chloride ion | PoSSuM | |||
NA | Sodium ion | PoSSuM |
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Download interaction data: 5MIM
Structure summary
Code : | 5MIM PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE | ||||||||||||
Title : | Xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n | ||||||||||||
Release Data : | 2017-05-10 | ||||||||||||
Compound : |
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Authors : | Dahms, S.O., Guan-Sheng, J., Than, M.E. | ||||||||||||
Keywords : | proprotein convertase, inhibitor, protease, complex, hydrolase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.900 Å ) | ||||||||||||
Citation : |
Structural Studies Revealed Active Site Distortions of Human Furin by a Small Molecule Inhibitor.
Dahms, S.O.,Jiao, G.S.,Than, M.E.
PubMed: 28402100 |
Reaction
Chain : | A | ||||||||
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UniProt : | P09958 (FURIN_HUMAN) | ||||||||
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