Het-PDB Navi2 (PDB: 5M6D)

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Ligands
Code	Name	Link
ACY	Acetic acid	PoSSuM
CA	Calcium ion	PoSSuM
CL	Chloride ion	PoSSuM
GOL	Glycerol	PoSSuM

Non-standard Residues
Code	Name	Show
CSU	Cysteine-S-sulfonic acid

Glycosylation
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Modification
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Download interaction data: 5M6D

Code :

5M6D PDBj RCSB PDB PDBe

Header :

OXIDOREDUCTASE

Title :

Streptococcus pneumoniae Glyceraldehyde-3-Phosphate Dehydrogenase (SpGAPDH) crystal structure

Release Data :

2017-01-11

Compound :

mol_id	molecule	chains
1	Glyceraldehyde-3-phosphate dehydrogenase	A,B
	ec: 1.2.1.- other_details: The active site cystein is oxidized, this why there seems to be a mismatch between sequence and coordinates, but this is not the case

Source :

mol_id	organism_scientific	expression_system
1	Streptococcus pneumoniae (taxid:1313)	Escherichia coli (taxid:469008)
	gene: gapdh, gap, gapA, gapA_3, ERS003549_02320, ERS019166_02194, ERS019420_02001, ERS019499_02096, ERS020135_02122, ERS020141_02006, ERS020142_02114, ERS020143_02138, ERS020145_02042, ERS020146_02116, ERS020147_02108, ERS020151_01255, ERS020155_02130, ERS020157_02177, ERS020178_05802, ERS020520_01871, ERS020522_01677, ERS020523_02061, ERS020524_02058, ERS020526_04928, ERS020526_06565, ERS020527_02055, ERS020531_01991, ERS020539_02263, ERS020541_02011, ERS020726_03159, ERS020822_04318, ERS020831_02217, ERS020873_02164, ERS020881_02198, ERS021047_02054, ERS021354_07537, ERS021360_02109, ERS021447_07389, ERS022199_02215, ERS022232_07453, ERS096208_02293, ERS232497_02152, ERS367628_02144, ERS367811_01576, ERS394170_00349, ERS409165_02221, ERS409372_02114, ERS409444_01606, ERS455085_02183, ERS515225_02154, SpnNT_02067 expression_system_strain: BL21(DE3) expression_system_variant: CodonPlus-RIL

Authors :

Gaboriaud, C., Moreau, C.P., Di Guilmi, A.M.

Keywords :

GAPDH, host/pathogen, plasminogen binding, oxidoreductase

Exp. method :

X-RAY DIFFRACTION ( 2.000 Å )

Citation :

Deciphering Key Residues Involved in the Virulence-promoting Interactions between Streptococcus pneumoniae and Human Plasminogen.

Moreau, C.,Terrasse, R.,Thielens, N.M. et al.
(2017) J. Biol. Chem. 292 : 2217 - 2225

PDB ID: 5M6D