PDB ID: 5LIY
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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DQP | {5-chloro-2-[(pentabromobenzyl)carbamoyl]phenoxy}acetic acid | PoSSuM | |||
EDO | 1,2-ethanediol | PoSSuM | |||
NAP | Nadp nicotinamide-adenine-dinucleotide phosphate | PoSSuM |
Code | Name | Show |
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MLY | N-dimethyl-lysine | |
MLZ | N-methyl-lysine |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 5LIY
Structure summary
Code : | 5LIY PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE | ||||||||||||
Title : | Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor MK204 | ||||||||||||
Release Data : | 2016-10-12 | ||||||||||||
Compound : |
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Source : |
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Authors : | Cousido-Siah, A., Ruiz, F.X., Mitschler, A., Fanfrlik, J., Kamlar, M., Vesely, J., Hobza, P., Podjarny, A. | ||||||||||||
Keywords : | alpha-beta TIM barrel, cytosol, aldo-keto reductase, halogenated ligand, oxidoreductase | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.05 Å ) | ||||||||||||
Citation : |
IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors.
Cousido-Siah, A.,Ruiz, F.X.,Fanfrlik, J.
et al.
PubMed: 27359042 |
Reaction
Chain : | X | ||||||||||||||||||||||||||||||||||||||||||||||||
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UniProt : | O60218 (AK1BA_HUMAN) | ||||||||||||||||||||||||||||||||||||||||||||||||
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