Het-PDB Navi2 (PDB: 5JBQ)

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Ligands
Code	Name	Link
GDP	Guanosine-5'-diphosphate	PoSSuM
MG	Magnesium ion	PoSSuM
SO4	Sulfate ion	PoSSuM

Non-standard Residues
Code	Name	Show
05N	(3r,4r)-4-hydroxy-3-methyl-L-proline
6RK	4-azanylcyclohexane-1-carboxylic acid
BB6	(2z)-2-amino-3-sulfanylbut-2-enoic acid
BB9	(2z)-2-amino-3-sulfanylprop-2-enoic acid
H14	(2s,3r)-beta-hydroxy-phenylalanine
MH6	3-hydroxy-2-iminopropanoic acid

Glycosylation
Code	Name	Emphasize

Modification
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Download interaction data: 5JBQ

Code :

5JBQ PDBj RCSB PDB PDBe

Header :

RNA BINDING PROTEIN/ANTIMICROBIAL

Title :

EF-TU (ESCHERICHIA COLI) IN COMPLEX WITH THIOMURACIN ANALOG

Release Data :

2016-07-13

Compound :

mol_id	molecule	chains	synonym
1	Elongation factor Tu 1	A	EF-Tu 1,Bacteriophage Q beta RNA-directed RNA polymerase subunit III,P-43

mol_id	molecule	chains
2	THIOMURACIN ANALOG	B

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (strain K12) (taxid:83333)	Escherichia coli (taxid:562)
	strain: K12 gene: tufA, b3339, JW3301

mol_id	organism_scientific
2	Synthetic construct (taxid:32630)
	synthetic: yes

Authors :

Palestrant, D., Stams, T.

Keywords :

natural product inhibitor, elongation factor, RNA BINDING PROTEIN-ANTIMICROBIAL complex

Exp. method :

X-RAY DIFFRACTION ( 2.006 Å )

Citation :

Antibacterial and Solubility Optimization of Thiomuracin A.

LaMarche, M.J.,Leeds, J.A.,Brewer, J. et al.
(2016) J.Med.Chem. 59 : 6920 - 6928

PDB ID: 5JBQ