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Ligands
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04M 5-(morpholin-4-ylsulfonyl)-2-{[3-(octyloxy)benzyl]oxy}benzoic acid
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Glycosylation
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Code : 5HN7   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE/TRANSFERASE INHIBITOR
Title : Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH-1158
Release Data : 2016-09-07
Compound :
mol_id molecule chains
1 Farnesyl pyrophosphate synthase, putative A,B,C,D,E,F,G,H
Source :
mol_id organism_scientific expression_system
1 Plasmodium vivax  (taxid:126793) ESCHERICHIA COLI  (taxid:469008)
strain: Salvador I
gene: PVX_092040
expression_system_strain: BL21(DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: P15-TEV-LIC
Authors : Liu, Y.-L., Zhang, Y., Oldfield, E.
Keywords : TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX
Exp. method : X-RAY DIFFRACTION ( 2.15 Å )
Citation :

Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase.

G Ricci, C.,Liu, Y.L.,Zhang, Y.  et al.
(2016)  Biochemistry  55 : 5180 - 5190

PubMed: 27564465
DOI: 10.1021/acs.biochem.6b00398

Chain : A, B, C, D, E, F, G, H
UniProt : A5K4U6 (A5K4U6_PLAVS)
Reaction : -