Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
AS 2-deoxy-adenosine -5'-thio-monophosphate
GOL Glycerol
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
ZN Zinc ion
Code : 5FBC
Header : HYDROLASE
Title : S1 nuclease from Aspergillus oryzae in complex with 2'-deoxyadenosine-5'-thio-monophosphate (5'dAMP(S)).
Release Data : 2016-12-28
Compound :
mol_id molecule chains synonym
1 Nuclease S1 A Deoxyribonuclease S1,Endonuclease S1,Single-stranded-nucleate endonuclease
ec: 3.1.30.1
other_details: Mature protein without signal sequence.
Source :
mol_id organism_scientific organism_common expression_system
1 Aspergillus oryzae RIB40  (taxid:510516) Yellow koji mold Aspergillus oryzae  (taxid:5062)
gene: nucS, AO090001000075
Authors : Koval, T., Oestergaard, L.H., Dohnalek, J.
Keywords : Endonuclease, Zinc dependent, Complex, hydrolase
Exp. method : X-RAY DIFFRACTION ( 1.75 Å )
Citation :

Structural and Catalytic Properties of S1 Nuclease from Aspergillus oryzae Responsible for Substrate Recognition, Cleavage, Non-Specificity, and Inhibition.

Koval, T.,stergaard, L.H.,Lehmbeck, J.  et al.
(2016)  PLoS ONE  11 : e0168832 - e0168832

PubMed: 28036383
DOI: 10.1371/journal.pone.0168832

Chain : A
UniProt : P24021 (NUS1_ASPOR)
Reaction : Endonucleolytic cleavage to 5'- phosphomononucleotide and 5'-phosphooligonucleotide end-products.