Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
5UE [(2~{R})-1-[(4-ethanoyl-1,3-thiazol-2-yl)amino]-1-oxidanylidene-propan-2-yl]azanium
CL Chloride ion
SO4 Sulfate ion
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 5F36   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of the bromodomain of human ATAD2 in complex with Compound A12
Release Data : 2016-12-14
Compound :
mol_id molecule chains synonym
1 ATPase family AAA domain-containing protein 2 A AAA nuclear coregulator cancer-associated protein,ANCCA
ec: 3.6.1.3
fragment: UNP residues 981-1108
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: ATAD2, L16, PRO2000
Authors : Dong, J., Caflisch, A.
Keywords : HYDROLASE INHIBITOR Complex, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.5000 Å )
Citation :

Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers.

Dolbois, A.,Batiste, L.,Wiedmer, L.  et al.
(2020)  Acs Med.Chem.Lett.  11 : 1573 - 1580

PubMed: 32832026
DOI: 10.1021/acsmedchemlett.0c00080

Chain : A
UniProt : Q6PL18 (ATAD2_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
ATP + H2O = ADP + H(+) + phosphate - -
-