Het-PDB Navi2 (PDB: 5E7Z)

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Ligands
Code	Name	Link
DPN	D-phenylalanine	PoSSuM
DTR	D-tryptophan	PoSSuM
GOL	Glycerol	PoSSuM
MN	Manganese (II) ion	PoSSuM
SO4	Sulfate ion	PoSSuM
TRP	Tryptophan	PoSSuM

Non-standard Residues
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Download interaction data: 5E7Z

Code :

5E7Z PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis in complex with D/L-tryptophan and D-phenylalanine

Release Data :

2016-06-01

Compound :

mol_id	molecule	chains
1	3-deoxy-D-arabinoheptulosonate-7-phosphate synthase	A,B
	ec: 2.5.1.54

Source :

mol_id	organism_scientific	expression_system
1	Mycobacterium tuberculosis (taxid:1773)	Escherichia coli (taxid:562)
	gene: aroG_1, ERS024751_03564, ERS094182_00944, ERS124362_02783

Authors :

Reichau, S., Jiao, W., Parker, E.J.

Keywords :

shikimate pathway, allosteric regulation, transferase

Exp. method :

X-RAY DIFFRACTION ( 2.40 Å )

Citation :

Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis Using -Amino Acids.

Reichau, S.,Blackmore, N.J.,Jiao, W. et al.
(2016) Plos One 11 : e0152723 - e0152723

PDB ID: 5E7Z