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Ligands
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5R7 (2~{S},3~{R})-3-methyl-2-[(2~{S},3~{R})-3-oxidanyl-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid
FLC Citrate anion
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Code : 5CTN   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Structure of BPu1 beta-lactamase
Release Data : 2015-11-25
Compound :
mol_id molecule chains
1 Beta-lactamase A,B
ec: 3.5.2.6
Source :
mol_id organism_scientific expression_system
1 Bacillus pumilus  (taxid:1408) Escherichia coli  (taxid:562)
gene: BPUM_2340
Authors : Smith, C.A., Vakulenko, S.B.
Keywords : hydrolase, beta-lactamase
Exp. method : X-RAY DIFFRACTION ( 1.3500 Å )
Citation :

Class D beta-lactamases do exist in Gram-positive bacteria.

Toth, M.,Antunes, N.T.,Stewart, N.K.  et al.
(2016)  Nat.Chem.Biol.  12 : 9 - 14

PubMed: 26551395
DOI: 10.1038/nchembio.1950

Chain : A, B
UniProt : A8FFI9 (A8FFI9_BACP2)
Reaction: EC: Evidence:
Physiological Direction:
a beta-lactam + H2O = a substituted beta-amino acid 3.5.2.6 RuleBase:RU361140
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