Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
FJS N-{3-[2,4-dihydroxy-5-(isoquinolin-4-yl)phenyl]-4-(4-methoxyphenyl)-1,2-oxazol-5-yl}cyclopropanecarboxamide
Code : 5CF0
Header : CHAPERONE/CHAPERONE INHIBITOR
Title : Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ6
Release Data : 2016-07-13
Compound :
mol_id molecule chains synonym
1 Heat shock protein HSP 90-alpha A Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38
fragment: N-terminal domain, UNP residues 9-236
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: HSP90AA1, HSP90A, HSPC1, HSPCA
Authors : Li, J., Shi, F., Xiong, B., He, J.H.
Keywords : Heat shock protein 90, N-terminal domain, inhibitor, CHAPERONE-CHAPERONE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 1.800 Å )
Citation :

FS23 binds to the N-terminal domain of human Hsp90: A novel small inhibitor for Hsp90

Li, J.,Shi, F.,Chen, D.-Q.  et al.
(2015)  Nucl.Sci.Tech.  26 : 060502 - 060502

DOI: 10.13538/j.1001-8042/nst.26.060503

Chain : A
UniProt : P07900 (HS90A_HUMAN)
Reaction : -