Het-PDB Navi2 (PDB: 5CC2)

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Ligands
Code	Name	Link
CKA	7-chlorokynurenic acid	PoSSuM
CL	Chloride ion	PoSSuM
GOL	Glycerol	PoSSuM

Non-standard Residues
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Download interaction data: 5CC2

Code :

5CC2 PDBj RCSB PDB PDBe

Header :

SIGNALING PROTEIN

Title :

STRUCTURE OF THE LIGAND-BINDING DOMAIN OF THE IONOTROPIC GLUTAMATE RECEPTOR-LIKE GLUD2 IN COMPLEX WITH 7-CKA

Release Data :

2015-12-30

Compound :

mol_id	molecule	chains	synonym
1	Glutamate receptor ionotropic, delta-2	A	GluR delta-2 subunit
	fragment: UNP residues 441-551,UNP residues 664-813

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Rattus norvegicus (taxid:10116)	Rat	Escherichia coli K-12 (taxid:83333)
	gene: Grid2 expression_system_variant: ORIGAMI 2 expression_system_vector_type: plasmid expression_system_plasmid: PET28

Authors :

Naur, P., Gajhede, M., Kastrup, J.S.

Keywords :

Ionotropic glutamate receptor, GluD2, ligand binding domain, NMDA receptor antagonist, signaling protein

Exp. method :

X-RAY DIFFRACTION ( 2.501 Å )

Citation :

Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors.

Kristensen, A.S.,Hansen, K.B.,Naur, P. et al.
(2016) Mol.Pharmacol. 89 : 253 - 262

Ionotropic glutamate-like receptor delta2 binds D-serine and glycine.

Naur, P.,Hansen, K.B.,Kristensen, A.S. et al.
(2007) Proc. Natl. Acad. Sci. U.S.A. 104 : 14116 - 14121

PDB ID: 5CC2