PDB ID: 5C5R
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
ZN | Zinc ion | PoSSuM | |||
0E1 | (7r)-2-hydroxy-7-(propan-2-yl)-7,8-dihydro-5h-pyrano[4,3-B]pyridine-3-carbonitrile | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
Code | Name | Show |
---|
Code | Name | Emphasize |
---|
Code | Name | Show |
---|
Download interaction data: 5C5R
Structure summary
Code : | 5C5R PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||||||||||||||
Title : | CRYSTAL STRUCTURE OF HUMAN TANKYRASE-2 IN COMPLEX WITH A PYRANOPYRIDONE INHIBITOR | ||||||||||||||||||||||||
Release Data : | 2015-08-12 | ||||||||||||||||||||||||
Compound : |
|
||||||||||||||||||||||||
Source : |
|
||||||||||||||||||||||||
Authors : | Lukacs, C.M., Janson, C.A. | ||||||||||||||||||||||||
Keywords : | WNT-SIGNALLING, BETA-CATENIN, PARP-DOMAIN, ADP-RIBOSYLATION, AXIN, TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.55 Å ) | ||||||||||||||||||||||||
Citation : |
Fragment-Based Drug Design of Novel Pyranopyridones as Cell Active and Orally Bioavailable Tankyrase Inhibitors.
de Vicente, J.,Tivitmahaisoon, P.,Berry, P.
et al.
PubMed: 26396691 |
Reaction
Chain : | C, D | ||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProt : | Q9H2K2 (TNKS2_HUMAN) | ||||||||||||||||
|