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Ligands
Code Name Style Show Link
NI Nickel (II) ion
AKG 2-oxoglutaric acid
FYU 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
Non-standard Residues
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Glycosylation
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Code : 5C3S   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG and 5-formyluracil (5fU)
Release Data : 2015-10-21
Compound :
mol_id molecule chains
1 Thymine dioxygenase A,B,C,D
Source :
mol_id organism_scientific expression_system
1 Neurospora crassa  (taxid:5141) Escherichia coli  (taxid:562)
strain: ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987
gene: NCU06416
expression_system_strain: BL21(DE3) Codon Plus
expression_system_vector_type: plasmid
expression_system_plasmid: pET-28a
Authors : Li, W., Zhang, T., Ding, J.
Keywords : dioxygenase, substrate C, DSBH fold, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.15 Å )
Citation :

Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi

Li, W.,Zhang, T.,Ding, J.
(2015)  Nucleic Acids Res.  43 : 10026 - 10038

PubMed: 26429971
DOI: 10.1093/nar/gkv979

Chain : A, B, C, D
UniProt : Q7RYZ9 (Q7RYZ9_NEUCR)
Reaction : -