Het-PDB Navi2 (PDB: 5B3R)

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Ligands
Code	Name		Style	Show	Link
ZN	Zinc ion				PoSSuM
CIT	Citric acid				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 5B3R

Code :

5B3R PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal structure of metallo-beta-lactamase IMP-18 from Pseudomonas aeruginosa

Release Data :

2017-02-15

Compound :

mol_id	molecule	chains	synonym
1	IMP-18	A,B	Metallo beta-lactamase,Metallo-beta-lactamase IMP-18
	ec: 3.5.2.6

Source :

mol_id	organism_scientific	expression_system
1	Pseudomonas aeruginosa (taxid:287)	Escherichia coli (taxid:562)
	gene: IMP-18, blaIMP-18, blaimp-18, imp-18 expression_system_vector_type: plasmid

Authors :

Shimizu-Ibuka, A., Ishii, Y.

Keywords :

metallo-beta-lactamase, hydrolase, antibiotic resistance

Exp. method :

X-RAY DIFFRACTION ( 2.00 Å )

Citation :

Structural and Mutagenic Analysis of Metallo-beta-Lactamase IMP-18

Furuyama, T.,Nonomura, H.,Ishii, Y. et al.
(2016) Antimicrob. Agents Chemother. 60 : 5521 - 5526

Chain :

A, B

UniProt :

Q5U807 (Q5U807_PSEAI)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
a beta-lactam + H2O = a substituted beta-amino acid	3.5.2.6	ARBA:ARBA00001526
a beta-lactam + H2O = a substituted beta-amino acid	-	ARBA:ARBA00001526

PDB ID: 5B3R