Het-PDB Navi2 (PDB: 5A5P)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name	Link
EDO	1,2-ethanediol	PoSSuM
JTF	8-{[2-(dimethylamino)ethyl]amino}-3-methyl-1,2-dihydroquinolin-2-one	PoSSuM
SO4	Sulfate ion	PoSSuM

Non-standard Residues
Code	Name	Show

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 5A5P

Code :

5A5P PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

Crystal structure of human ATAD2 bromodomain in complex with 8-2-(dimethylamino)ethylamino-3-methyl-1,2-dihydroquinolin-2-one

Release Data :

2015-07-22

Compound :

mol_id	molecule	chains	synonym
1	ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2	A	AAA NUCLEAR COREGULATOR CANCER-ASSOCIATED PROTEIN, ANCCA, HUMAN ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2
	ec: 3.6.1.3 fragment: BROMODOMAIN, RESIDUES 981-1108

Source :

mol_id	organism_scientific	organism_common	expression_system
1	HOMO SAPIENS (taxid:9606)	HUMAN	ESCHERICHIA COLI (taxid:562)
	expression_system_vector_type: PLASMID expression_system_plasmid: PNIC28-BSA4

Authors :

Chung, C., Bamborough, P., Demont, E.

Keywords :

HYDROLASE, INHIBITOR, ATAD2, BROMODOMAIN, EPIGENETICS, ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 2

Exp. method :

X-RAY DIFFRACTION ( 2.03 Å )

Citation :

Fragment-Based Discovery of Low-Micromolar Atad2 Bromodomain Inhibitors.

Demont, E.H.,Chung, C.,Furze, R.C. et al.
(2015) J.Med.Chem. 58 : 5649

Chain :

UniProt :

Q6PL18 (ATAD2_HUMAN)

PDB ID: 5A5P