PDB ID: 5ZZ4
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Structure summary
Code : | 5ZZ4 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal structure of bruton'S tyrosine kinase in complex with inhibitor 2e | ||||||||||||
Release Data : | 2018-09-26 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kawahata, W., Asami, T., Irie, T., Kiyoi, T., Taniguchi, H., Asamitsu, Y., Inoue, T., Miyake, T., Sawa, M. | ||||||||||||
Keywords : | protein kinase, inhibitor complex, non-covalent, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.9000 Å ) | ||||||||||||
Citation : |
Design and Synthesis of Novel Amino-triazine Analogues as Selective Bruton's Tyrosine Kinase Inhibitors for Treatment of Rheumatoid Arthritis.
Kawahata, W.,Asami, T.,Kiyoi, T.
et al.
PubMed: 30216722 |
Reaction
Chain : | A, B, C, D, E, F | ||||||||
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UniProt : | Q06187 (BTK_HUMAN) | ||||||||
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