Het-PDB Navi2 (PDB: 5ZXI)

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Ligands
Code	Name		Style	Show	Link
9LU	6-[2-({2-[4-(furan-2-yl)phenyl]-5-methyl-1h-imidazol-1-yl}methyl)phenoxy]hexanoic acid				PoSSuM

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Download interaction data: 5ZXI

Code :

5ZXI PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Co-crystal structure of an Inhibitor in complex with human PPARdelta LBD

Release Data :

2019-04-03

Compound :

mol_id	molecule	chains	synonym
1	Peroxisome proliferator-activated receptor delta	A,B	PPAR-delta,NUCI,Nuclear hormone receptor 1,NUC1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferator-activated receptor beta,PPAR-beta

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli K-12 (taxid:83333)
	gene: PPARD, NR1C2, PPARB

Authors :

Rani, S.T., Laxminarasimhan, A., Senaiar, R.S., Krishnamurthy, N.

Keywords :

PPARdelta, Inhibitor compound Co-Crystal structure, TRANSCRIPTION

Exp. method :

X-RAY DIFFRACTION ( 2.10 Å )

Citation :

Selective PPAR delta Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD).

Lagu, B.,Kluge, A.F.,Tozzo, E. et al.
(2018) ACS Med Chem Lett 9 : 935 - 940

PDB ID: 5ZXI