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Ligands
Code Name Style Show Link
9JU N-(adamantan-1-yl)-1-(5-hydroxypentyl)-4-methyl-5-phenyl-1h-pyrazole-3-carboxamide
EPE 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
OLA Oleic acid
OLC (2r)-2,3-dihydroxypropyl (9z)-octadec-9-enoate
PEG Di(hydroxyethyl)ether
PG4 Tetraethylene glycol
SO4 Sulfate ion
Non-standard Residues
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Glycosylation
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Code : 5ZTY   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : Crystal structure of human G protein coupled receptor
Release Data : 2019-01-30
Compound :
mol_id molecule chains synonym
1 G protein coupled receptor,T4 lysozyme,G protein coupled receptor A Lysis protein,Lysozyme
ec: 3.2.1.17
fragment: UNP residues 21-222,UNP residues 1-161,UNP residues 235-352
mutation: G78L, T127A, T153l,C1053T, C1096A,R242E, G304E
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
Authors : Li, X.T., Hua, T., Wu, L.J., Liu, Z.J.
Keywords : GPCR, cell signaling, ligand design, MEMBRANE PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.8000 Å )
Citation :

Crystal Structure of the Human Cannabinoid Receptor CB2

Li, X.,Hua, T.,Vemuri, K.  et al.
(2019)  Cell  176 : 459 - 467.e13

PubMed: 30639103
DOI: 10.1016/j.cell.2018.12.011

Chain : A
UniProt : P34972 (CNR2_HUMAN)
Reaction : -
Chain : A
UniProt : D9IEF7 (D9IEF7_BPT4)
Reaction: EC: Evidence:
Physiological Direction:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. 3.2.1.17 ARBA:ARBA00000632, HAMAP-Rule:MF_04110, RuleBase:RU003788
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