Het-PDB Navi2 (PDB: 5ZSM)

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Ligands
Code	Name		Style	Show	Link
9K9	2-amino-9-[(2s,3ar,4r,6r,6ar)-2-hydroxy-6-(hydroxymethyl)-2-oxotetrahydro-2h-2lambda~5~-furo[3,4-D][1,3,2]dioxaphosphol-4-yl]-3,9-dihydro-6h-purin-6-one				PoSSuM
SO4	Sulfate ion				PoSSuM

Non-standard Residues
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Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

Modification
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Download interaction data: 5ZSM

Code :

5ZSM PDBj RCSB PDB PDBe

Header :

IMMUNE SYSTEM

Title :

Crystal structure of monkey TLR7 in complex with GGUCCC

Release Data :

2019-01-30

Compound :

mol_id	molecule	chains
1	Toll-like receptor 7	B,A
	fragment: UNP residues 27-839 mutation: N167Q,N389Q,N488Q,N799Q

mol_id	molecule	chains
2	RNA (5'-R(GPUPCPCP*C)-3')	D,E

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Macaca mulatta (taxid:9544)	Rhesus macaque	Drosophila melanogaster (taxid:7227)
	gene: TLR7

mol_id	organism_scientific
2	Synthetic construct (taxid:32630)
	synthetic: yes

Authors :

Zhang, Z., Ohto, U., Shimizu, T.

Keywords :

Innate immunity Toll-like receptors, IMMUNE SYSTEM

Exp. method :

X-RAY DIFFRACTION ( 2.50 Å )

Citation :

Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands.

Zhang, Z.,Ohto, U.,Shibata, T. et al.
(2018) Cell Rep 25 : 3371 - 3381.e5

PDB ID: 5ZSM