Het-PDB Navi2 (PDB: 5ZQU)

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Ligands
Code	Name		Style	Show	Link
9HF	1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)benzotriazole-5-carboxylic acid				PoSSuM
BR	Bromide ion				PoSSuM

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Download interaction data: 5ZQU

Code :

5ZQU PDBj RCSB PDB PDBe

Header :

TRANSCRIPTION

Title :

Crystal structure of tetrameric RXRalpha-LBD complexed with partial agonist CBt-PMN

Release Data :

2019-02-27

Compound :

mol_id	molecule	chains	synonym
1	Retinoic acid receptor RXR-alpha	A,B,C,D	Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli BL21(DE3) (taxid:469008)
	gene: RXRA, NR2B1 expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: pET28a

Authors :

Miyashita, Y., Numoto, N., Arulmozhiraja, S., Nakano, S., Matsuo, N., Shimizu, K., Kakuta, H., Ito, S., Ikura, T., Ito, N., Tokiwa, H.

Keywords :

extended form, multiple conformation, nuclear receptor, retinoid x receptor, TRANSCRIPTION

Exp. method :

X-RAY DIFFRACTION ( 2.60038789589 Å )

Citation :

Dual conformation of the ligand induces the partial agonistic activity of retinoid X receptor alpha (RXR alpha ).

Miyashita, Y.,Numoto, N.,Arulmozhiraja, S. et al.
(2019) FEBS Lett. 593 : 242 - 250

PDB ID: 5ZQU