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Ligands
Code Name Style Show Link
SO4 Sulfate ion
9EF N-[2-(acetylamino)ethyl]-N~3~-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide
Non-standard Residues
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Glycosylation
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Code : 5ZK4   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : The structure of DSZS acyltransferase with carrier protein
Release Data : 2018-06-13
Compound :
mol_id molecule chains synonym
1 DisD protein A,B DszD
mutation: S86C
mol_id molecule chains synonym
2 DisA protein C,D DszA
Source :
mol_id organism_scientific organism_common expression_system
1 Sorangium cellulosum  (taxid:56) Polyangium cellulosum Escherichia coli BL21(DE3)  (taxid:469008)
gene: dszD, disD
expression_system_strain: BL21(DE3)
expression_system_vector_type: Plasmid
expression_system_plasmid: PCold I
mol_id organism_scientific organism_common expression_system
2 Sorangium cellulosum  (taxid:56) Polyangium cellulosum Escherichia coli BL21(DE3)  (taxid:469008)
gene: dszA, disA
expression_system_strain: BL21(DE3)
expression_system_vector_type: Plasmid
expression_system_plasmid: pET28
Authors : Miyanaga, A., Ouchi, R., Kudo, F., Eguchi, T.
Keywords : TRANSFERASE, ACYL CARRIER PROTEIN, POLYKETIDE BIOSYNTHESIS
Exp. method : X-RAY DIFFRACTION ( 2.03 Å )
Citation :

Structural basis of protein-protein interactions between a trans-acting acyltransferase and acyl carrier protein in polyketide disorazole biosynthesis

Miyanaga, A.,Ouchi, R.,Ishikawa, F.  et al.
(2018)  J. Am. Chem. Soc.  140 : 7970 - 7978

PubMed: 29870659
DOI: 10.1021/jacs.8b04162

Chain : A, B
UniProt : Q4U443 (Q4U443_SORCE)
Reaction: EC: Evidence:
Physiological Direction:
holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP] 2.3.1.39 ARBA:ARBA00000936
-
Chain : C, D
UniProt : Q4U447 (Q4U447_SORCE)
Reaction : -