Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
9EO (3z)-N-[(1s)-2-hydroxy-1-phenylethyl]-3-[(1h-imidazol-2-yl)(phenyl)methylidene]-2-oxo-2,3-dihydro-1h-indole-5-carboxamide
BCT Bicarbonate ion
EDO 1,2-ethanediol
TRS 2-amino-2-hydroxymethyl-propane-1,3-diol
Non-standard Residues
Code Name Show
SEP Phosphoserine
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 5ZJW   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal Structure of PAK4 in complex with inhibitor CZg353
Release Data : 2019-04-03
Compound :
mol_id molecule chains synonym
1 Serine/threonine-protein kinase PAK 4 A p21-activated kinase 4,PAK-4
ec: 2.7.11.1
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli BL21(DE3)  (taxid:469008)
gene: PAK4, KIAA1142
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pSUMOH10
Authors : Zhao, F., Li, H.
Keywords : ATP binding pocket, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.7980 Å )
Citation :

Crystal Structure of PAK4 in complex with inhibitor CZg353

Zhao, F.,Li, H.
To be published 

Chain : A
UniProt : O96013 (PAK4_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl- [protein] 2.7.11.1 -
-
ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L- threonyl-[protein] 2.7.11.1 -
-