Het-PDB Navi2 (PDB: 5ZJF)

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Ligands
Code	Name		Style	Show	Link
9G9	5,5'-[(2r,3s)-2,3-dimethylbutane-1,4-diyl]bis(2h-1,3-benzodioxole)				PoSSuM

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Download interaction data: 5ZJF

Code :

5ZJF PDBj RCSB PDB PDBe

Header :

OXIDOREDUCTASE

Title :

LDHA-MA

Release Data :

2019-07-24

Compound :

mol_id	molecule	chains	synonym
1	L-lactate dehydrogenase A chain	A,B,C,D,E,F,G,H,I,J,K,L	LDH-A,Cell proliferation-inducing gene 19 protein,LDH muscle subunit,LDH-M,Renal carcinoma antigen NY-REN-59
	ec: 1.1.1.27

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: LDHA, PIG19

Authors :

Han, C.W., Jang, S.B.

Keywords :

LDHA, inhibitor, machilin a, OXIDOREDUCTASE

Exp. method :

X-RAY DIFFRACTION ( 2.602 Å )

Citation :

Machilin A Inhibits Tumor Growth and Macrophage M2 Polarization Through the Reduction of Lactic Acid.

Chung, T.-W.,Kim, E.-Y.,Han, C.W. et al.
(2019) Cancers (Basel) 11

Chain :

A, B, C, D, E, F, G, H, I, J, K, L

UniProt :

P00338 (LDHA_HUMAN)

PDB ID: 5ZJF