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Ligands
Code Name Style Show Link
9EL (2s,3r)-2-amino-9-methoxy-3-(2,4,5-trifluorophenyl)-2,3-dihydro-1h-naphtho[2,1-B]pyran-8-carbonitrile
Non-standard Residues
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Glycosylation
Code Name Emphasize
MAN Alpha-D-mannopyranose
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
Code Name Show
Code : 5ZID   PDBj   RCSB PDB   PDBe
Header : HYDROLASE
Title : Crystal Structure of human DPP-IV in complex with HL2
Release Data : 2019-03-20
Compound :
mol_id molecule chains synonym
1 Dipeptidyl peptidase 4 A,B ADABP,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,DPP IV,T-cell activation antigen CD26,TP103
ec: 3.4.14.5
fragment: Dipeptidyl peptidase 4 soluble form
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Spodoptera frugiperda  (taxid:7108)
gene: DPP4, ADCP2, CD26
Authors : Zhu, L., Li, H., Wu, F.
Keywords : INHIBITOR COMPLEX, DPP-4, HYDROLASE
Exp. method : X-RAY DIFFRACTION ( 3.00 Å )
Citation :

Crystal Structure of human DPP-IV in complex with HL2

Zhu, L.,Li, H.,Wu, F.
To Be Published 

Chain : A, B
UniProt : P27487 (DPP4_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline. 3.4.14.5 PROSITE- ProRule:PRU10084, PubMed:10593948
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