PDB ID: 5ZHL
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Structure summary
Code : | 5ZHL PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE | ||||||||||||
Title : | Crystal structure of TrmD from Mycobacterium tuberculosis in complex with active-site inhibitor | ||||||||||||
Release Data : | 2019-03-06 | ||||||||||||
Compound : |
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Source : |
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Authors : | Zhong, W., Pasunooti, K.K., Balamkundu, S., Wong, Y.W., Nah, Q., Liu, C.F., Lescar, J., Dedon, P.C. | ||||||||||||
Keywords : | tRNA methyltransferase, TRANSFERASE | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.25 Å ) | ||||||||||||
Citation : |
Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism.
Zhong, W.,Pasunooti, K.K.,Balamkundu, S.
et al.
PubMed: 31442049 |
Reaction
Chain : | A | ||||||||
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UniProt : | P9WFY6 (TRMD_MYCTO) | ||||||||
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